Study of methods to prevent leakage of drug solution into subcutaneous tissue at site of intramuscular injection

使用Z-track方法，我检查了是否有可能防止药物溶液在肌肉注射部位渗漏到皮下组织中。在护士中进行的调查显示，人们普遍认为这种方法不能防止这种泄漏。我分析了使用z轨迹法时皮肤表面和皮下组织移动的距离，发现根据该方法的原理很难充分移动皮下组织层。此外，用兔子做的实验表明，z径迹法对防止渗漏到皮下组织并不是特别有效。

Using the Z-track method, I examined whether it was possible to prevent leakage of drug solution into subcutaneous tissue at sites of intramuscular injection. Inquiry among nurses revealed a widespread impression that the method did not prevent such leakage. I analyzed the distance moved by the skin surface and subcutaneous tissue while applying the Z-track method, and found that it was difficult to move the subcutaneous tissue layer sufficiently according to the principle of the method. Furthermore, an experiment using rabbits showed that the Z-track method was not particularly effective for prevention of leakage into subcutaneous tissue.