Measurement of pressure distribution under the denture base and observation of bone metabolic activity under denture base using NaF-PET/CT in vivo

为了研究义齿植入对义齿基托下残脊骨代谢的影响，我们在植入可摘局部义齿（RPD）后第0天、第1周、第6周和第13周分别拍摄了氟-18 NaF正电子发射断层扫描（NaF- pet）和x线计算机断层扫描（CT）。RPD分娩后，x线CT图像显示RPD下骨结构随时间无明显变化，RPD下骨CT值无变化。然而，在RPD分娩后，尽管义齿支持组织没有出现疼痛和炎症等临床并发症，但RPD下骨的PET标准化摄取值逐渐增加。结果表明，佩戴义齿后，义齿基托下骨周转率逐渐增加，但骨结构和骨体积没有变化。

To examine how denture insertion influenced the bone metabolism at the residual ridge beneath the denture base, Fluorine-18 NaF positron-emission tomography (NaF-PET) and X-ray computed tomography (CT) images were taken 0 day, 1 week, 6 weeks and 13 weeks after delivery of the removable partial denture (RPD). X-ray CT images showed no obvious change of bone structure beneath RPD with time after delivery of the RPD, and CT value at bone beneath RPD did not change. However, PET standardized uptake value at bone beneath RPD gradually increased after RPD delivery despite no clinical complications in the denture-supporting tissues, such as pain and inflammation. This result showed that wearing of the denture increase the bone turn over beneath the denture base gradually without the change of bone structure and volume.