Susceptibility-weighted MR imaging in misery perfusion in patients with ischemic cerebrovascular disease: comparison with 15O PET

在37例PET检测到灌注异常的患者中，30<15>例患者的磁共振成像显示狭窄闭塞病变的同侧大脑浅静脉和深静脉内明显低信号。24例PET检查无灌注异常的患者均<15>无脑静脉内明显低信号。磁敏感加权成像在显示脱氧血红蛋白浓度增加的明显低信号脑静脉方面优于GRE-EPI，但其表现上级。我们的研究结果表明磁共振加权成像有助于识别慢性脑血管病的不良灌注。在GRE-EPI上，由于急性栓塞闭塞而导致的进展性梗死中，常可见同侧大脑浅静脉和深静脉充血。

In 30 of the 37 patients with misery perfusion detected by ^<15>O PET, susceptibility-weighted MR imaging demonstrated prominently hypointense signal within the superficial and deep cerebral veins ipsilaterally in steno-occlusive lesions. None of the 24 patients without misery perfusion detected by ^<15>O PET showed prominently hypointense signal within the cerebral veins. Susceptibility-weighted imaging was superior to GRE-EPI for visualization of the prominently hypointense cerebral veins with increased deoxyhemoglobin concentration. Our results suggest that susceptibility-weighted imaging is helpful in identifying misery perfusion in chronic cerebrovascular disease.On GRE-EPI, engorgement of superficial and deep cerebral veins was frequently seen ipsilaterally in evolving infarction due to acute embolic occlusion.