Usefullness of novel boronated porphyrins for both BNCT and PDT

在硼化卟啉中，我们在术前的初始手术中将其作为PDD使用，并在术中照射时进行PDT，并且能够测量个体患者肿瘤的硼含量。因此，当我们在手术后进行BNCT时，考虑到了能够在适应症判断、剂量评估中使用该实际值的优点。由于硼化卟啉的可见性和对肿瘤的高蓄积性，该化合物在PDT和BNCT中均具有预期的治疗效果。

In the boronated porphyrin, we give it as a PDD use at initial surgery in preoperation and perform PDT as intraoperative irradiation and would be able to measure the boron contents of the tumor in the individual patient. An advantage to be able to use this actual value in a judgment of indication, dose assessment was, thereby, thought about when we performed BNCT following surgery. Because the boronated porphyrin is full of visibility and shows high accumulation for the tumor, this compound can expect effect of treatment in the both PDT and BNCT.