Measurement of Anisotropic Elastic Modulus of Bone Tissue Using X-ray Diffraction from HAp Crystals

在显微镜下，骨组织是羟基磷灰石（HAp）和胶原蛋白的复合物。骨组织的各向异性弹性受到骨组织中HAp微观结构的强烈影响，由于骨组织中的HAp具有晶体结构，因此采用x射线衍射测量其晶格应变。骨组织应力与晶格应变和HAp的体积分数有关。组织的弹性模量取决于HAp晶体的应变。本研究将x射线衍射技术应用于皮肤组织覆盖材料。当植入材料位于皮肤组织下时，可以用x射线衍射法测量植入材料的应变。

On the microscopic scale, bone tissue is a composite of hydroxyapatite (HAp) and collagen. Anisotropic elasticity of bone tissue is strongly influenced by the microscopic structure of the HAp in bone tissue, and as HAp in bone has a crystalline structure, X-ray diffraction is used to measure the crystal lattice strain. It was found that the bone tissue stress was related by the lattice strains and volume fraction of HAp. And elastic modulus of the tissue depended on the strain of HAp crystals. This study applied the X-ray diffraction to the skin tissue covered materials. The strain of the implanted material could be measured by this X-ray diffraction method when the material was located under the skin tissue.