Analysis of movement-related sympathetic responses reflecting volition of individuals with severe motor impairment

本研究的目的是发现人类的运动意志是否伴随着交感神经的激活，从而开发依赖于交感神经反应的辅助装置。研究自发性反应任务中肌电图发作与皮肤交感神经活动（SSNA）的时间关系。SSNA的发作不受提示的时间限制，而是与肌电图反应时间呈正相关。自发性握力实验中肌电图与SSNA爆发的间隔时间明显短于电刺激实验中SSNA爆发的潜伏期，略长于神经节后传导时间。我们的研究结果表明，中枢运动系统参与了对自主运动执行的交感俯伏肌反应。

The purpose of this study was to find out if the human volition to move is accompanied with sympathetic activation toward developing assistive devices relied on sympathetic responses. Temporal relationship between EMG onset and skin sympathetic nerve activity(SSNA) was investigated in voluntary reaction tasks. SSNA onset was not time-locked to the cue, but was instead positively correlated with EMG reaction time. The interval between the EMG and SSNA bursts in voluntary handgrip trials was significantly shorter than the latency of SSNA bursts in electrical stimulation trials, and slightly longer than the postganglionic conduction time. Our findings suggest that central motor systems are involved in the sympathetic sudomotor response to voluntary motor execution.