Basic research for biological monitoring in workers exposed to formaldehyde

甲醛在许多工业生产中都有使用，工人接触甲醛的浓度很难测量。为建立甲醛生物监测方法，研究了人体甲醛、甲醇暴露浓度与尿中甲醛、甲醇浓度的相关性。在甲醛职业暴露限值附近，个人甲醛暴露浓度与尿中甲醛、甲酸、甲醇浓度无相关性。采用问卷调查法对甲醛的刺激性进行了研究。刺激与个人甲醛浓度之间没有关系。

Formaldehyde are used at many industrial manufacture, and is hard to measure the formaldehyde exposure concentration to worker. For the reason of establish a biological monitoring method of formaldehyde, we had investigated the correlation between personal exposure concentration of formaldehyde and methanol and urinary concentration of them. There was no correlation between personal formaldehyde exposure concentration and urinary concentration of formaldehyde, formic acid and methanol at the concentration near the occupational exposure limit of formaldehyde. We also examined irritation of formaldehyde using questionnaire. No relation was seen between irritation and personal concentration of formaldehyde.