The study of new radiation therapy combined with high concentration ascorbic acid as to achieve high tumor local control rate

本研究旨在探讨抗坏血酸（阿萨）与放射线联合应用的临床应用价值。阿萨可诱导HL 60、HT 1080、SAS、A549细胞死亡，与X射线单独照射组相比，阿萨联合照射组活细胞数明显减少。提示X线和阿萨联合治疗对肿瘤细胞有较好的杀伤作用，其临床应用值得进一步研究。

This study was conducted to examine the utility of the combined use of ascorbic acid (AsA) and radiation in clinical applications. AsA induced cell death and the number of living cells significantly decreased after combined X-ray irradiation and AsA treatment in comparison with that after X-ray irradiation alone in four all cell lines (HL60, HT1080, SAS, A549). This result suggested that the combined X-ray and AsA treatment was effective against cancer cells and the clinical applications should be examined in the future.