Space and time-resolved analyses of radical reactions densely produced by heavy ion irradiation

为了增加高能重离子在纳米和先进医学中的应用，研究了重离子产生的自由基的反应。开发了一种短脉冲形成技术。用时间分辨光谱观察了自由基的反应依赖于入射离子的质量和能量，以及辐照后经过的时间。此外，通过蒙特卡罗模拟估算了细胞内的剂量分布和微观DNA损伤分布。

In order to increase applications of high energy heavy ions in nano- and advanced medical-sciences, reactions of radicals produced by heavy ions were investigated. A short pulse formation technology was developed. The reactions of radicals depending on mass and energy of the incident ion, and elapsed time just after irradiation were observed by a time-resolved spectroscopy. Furthermore, dose distributions in cell and microscopic DNA damage distributions were estimated by the Monte Carlo simulation.