Fluorescence detection of induction potential on chiral bio-macromolecule under pulsed magnetic field.

我们尝试用感生荧光染料来检测生物螺旋结构在脉冲磁场作用下的感应电势。将具有超螺旋结构的质粒DNA用银纳米颗粒包裹以增加电导率，然后与荧光素结合。将功能化的质粒DNA分散在生理盐水中，观察了脉冲磁场伴随的荧光变化。这种荧光变化发生在施加磁场的约100 μs延迟。有人认为，这是由于在螺旋结构中的脉冲磁场和感生磁动量之间的相互作用所引起的取向。

We examined to detect the induction potential on a bio-helical structure under pulsed magnetic field by using potential susceptible fluorescence dye. A plasmid DNA, which has supercoiled structure, was coated by Ag nanoparticles to increase the conductivity, and then was bounded with fluorescein. The functionalized plasmid DNA was dispersed in a saline and the fluorescence change accompanied with the pulsed magnetic field was observed. This fluorescence change took place with ～100 μs delay from the applied magnetic field. It was suggested that this is due to the orientation caused by the interaction between the pulsed magnetic field and the induced magnetic momentum in the helical structure.