Determination of accurate surgical margin using indocyanine green (ICG) and near infrared spectroscopy in thoracic surgery.

共检测24例（男21例，女3例），其中19例（79.17%）通过荧光法定位。前哨淋巴结的正确率为17 / 19（89.47%）。每例pN1和pN2，前哨淋巴结（大叶、叶间）和转移淋巴结（肺门、亚节段）不同。提示淋巴结转移至亚节段和肺门后，淋巴通路发生改变。否则从亚节段到肺门的淋巴通路充满肿瘤细胞，因此ICG无法到达肺门。这项新技术显示了肺癌淋巴结的有效识别。为了建立肺癌前哨淋巴结导航手术的策略，我们需要进一步的研究和分析。我们调查了19例大疱并检测了手术边缘。切缘阳性13例，阴性6例。14例大疱性气胸中有8例（57.1%）手术切缘阳性。与病理手术切缘的一致性为84.2%。认为荧光法在手术中估计手术切缘是有效的。

We performed twenty-four cases (male/21, female/3), and SN localization were identified in 19(79.17%) cases by fluorescence method. Accurate identification of sentinel node were 17 out of 19 (89.47%). Each one case of pN1 and pN2, sentinel lymph node (lobar, interlobar) and metastatic lymph node (hilar, subsegmental ) were different. It is suggested that the lymph pathway had been changed due to lymph node metastasis to subsegmental and hilar. Otherwise the lymph pathway from subsegmental to hilar was filled with tumor cells, so ICG could not arrive at hilar. The novel technique indicates efficient lymph node identification in lung cancer. To establish the strategy of sentinel lymph node navigation surgery in lung cancer, we need further studies and analysis.We investigated 19 cases of bulla and detected the surgical margin. Positive surgical margin were estimated 13 cases, and negative were 6 cases. Giant bulla cases and 8 out of 14 cases (57.1%) of pneumothorax showed positive surgical margin. Consistence with pathological surgical margin was 84.2%. It is considered that estimation of surgical margin during the operation by fluorescence method were effective.