A research and development of novel low-cytotoxic oral self-care methods for the patients who use denture adhesives.

采用纸片法检测了10种市售义齿清洁剂对白色念珠菌的抑菌活性。在这项实验中，我们测试了八种家庭护理清洁工和两种专业清洁工。每种家用清洁剂的抗菌活性均低于专业清洁剂，但仍足以满足临床使用要求，并通过皂洗法考察了5种家用清洁剂对乳膏型牙科粘合剂的去除效果。浸泡18h以上，几乎所有清洗剂的去除效果都大于纯净水。然而，临床上使用义齿清洁剂的时间还不到12小时，因此需要进一步研究开发能更有效地去除义齿粘附剂的新型义齿清洁剂。

We first analyzed antimicrobial activity of ten kinds of commercial denture cleaner against Candida albicans by disk method. We examined eight kinds of home-care cleaners and two kinds of professional cleaners in this experimentation. Antimicrobial activity of every home-care cleaner was effective enough for clinical usage although it was lower than that of professional cleaners.Moreover, we investigate removal activities of cream-type dental adhesives in five kinds of home care cleaners by soaping method. Removal effect in almost all of the cleaning agents was larger than purified water when soaking it for more than eighteen hours. However, we clinically use denture cleaner solution for less than twelve hours, so further studies are needed for the development of new denture cleaner which could remove denture adhesive more effectively.