Analysis of autonomic nerve by chromogranin A during locomotor respiratory coupling

我们研究了在运动呼吸耦合（LRC）过程中计算的自行车计力器踏板比率对通气指标和唾液嗜铬粒蛋白a的影响。这些受试者被分为两组。一组以每分钟50转的速度蹬车，另一组以每分钟40转的速度蹬车。首先，受试者在自主呼吸条件下以无氧阈值（at）蹬车10分钟，然后在LRC条件下进行相同的运动。LRC下50 rpm组出现持续性呼吸困难；然而，40转/分钟组呼吸频率和呼吸困难明显降低。人唾液嗜铬粒蛋白A水平与蹬车和呼吸的耦合无关。当自主呼吸时的呼吸频率小于LRC时，呼吸困难减轻，而当前者大于后者时，呼吸困难不减轻。尽管如此，我们无法阐明LRC对通气指标和人唾液嗜铬粒蛋白A的益处。

We studied the effect of cycle ergometer pedal ratio calculated during locomotor respiratory coupling (LRC) on ventilatory indicators and salivary chromogranin A. Twenty-five subjects participated in our study. These subjects were divided into 2 groups. One group performed pedaling at a rate of 50 rotations per minute (rpm), and the other group performed pedaling at 40 rpm. First, the subjects pedaled at anaerobic threshold(AT) under the spontaneous breathing condition for 10 min, and then performed the same exercise under LRC. The 50-rpm group showed persistent dyspnea under LRC; however, the 40-rpm group showed a significant decrease in the respiratory rate and dyspnea.Human salivary chromogranin A level was not related to coupling between pedaling and respiration. Dyspnea decreased when the breathing rate during spontaneous breathing was lesser than that during LRC, but did not decrease when the former was greater than the latter. Nonetheless, we could not clarify the benefit of LRC on ventilatory indicators and human salivary chromogranin A.