Effect of meal on postprandial change in heart rate, blood pressure and cardiac autonomic activity

一些流行病学数据表明，餐后血流动力学变化的有害影响，包括心率、血压和心脏自主神经活动。提高对这种血流动力学变化的认识应该有助于建议调整饮食，并提供能够限制膳食诱导的有害血流动力学后果的治疗方法。本研究的目的有三个方面：(1)阐明进食量对餐后血流动力学变化的影响；(2)比较一天中不同进餐时间的餐后血流动力学变化的差异；(3)比较糖尿病患者和健康人餐后血流动力学的变化。营养素摄入后胰岛素升高与餐后血流动力学改变有关，进食量可能对餐后血流动力学改变起重要作用。夜间进食(晚上11点)影响夜间心率节律和心脏自主神经活动，导致早晨血压升高。在相对早期的糖尿病患者中，观察到餐后中心血压和臂血压的下降。

Several epidemiological data suggest the deleterious influence of postprandial hemodynamic changes, including heart rate, blood pressure and cardiac autonomic activity. Improving the knowledge of such hemodynamicchanges should lead to advise diet modifications and to offer treatments able to limitmeal-induced deleterious hemodynamic consequences. The purpose of the investigation was threefold:(1) to clarify the effect of meal amount on postprandial hemodynamic changes(2) to compare the difference of postprandial hemodynamic changes at different dinner times of the day(3) to compare postprandial hemodynamic changes in diabetics with those of healthy persons. The increase in insulin after nutrient intake was associated with postprandial hemodynamic changes and meal amount might play the important role on postprandial hemodynamic changes. Nocturnal eating (at 11pm) affected the rhythm of heart rate and cardiac autonomic activity during night resulting the high blood pressure in the morning. In patients with diabetes mellitus in the relatively early stage, postprandial decrease in central blood pressure as well as in brachial blood pressurewas observed.