Utilization of biomass resources based on genome analyses of acetic acid bacteria

醋酸菌(AAB)的特点是能够将醇和糖醇转化为相应的有机酸。为了获得在高糖浓度下可行的新代谢系统，并建立一个理解AAB环境反应的模型系统，我们首先进行了比较基因组、转录组和蛋白质组分析，为了确定25个AAB的基因组DNA草稿序列，我们使用下一代测序仪进行了DNA测序、组装和基因提取。我们将介绍我们在高糖胁迫下代谢和基因调控的最新数据。

Acetic acid bacteria (AAB) are characterized by their ability to transform alcohols and sugar-alcohols into their corresponding organic acids. To acquire new metabolic systems practicable in high sugar concentration and to achieve a model system to comprehend environmental responses of AAB, we have performed comparative genome, transcriptome and proteome analyses First, to determine draft genome DNA sequences of 25 AAB, we carried out DNA sequencing, assembling and gene extraction by using a next generation sequencer. We will present our recent data for the metabolic and gene regulations by the stress of high glucose concentration.