Fundamental study on pathologic conditions of multiple chemical sensitivity

我们调查了百万本诊所“病室门诊”中多重化学敏感性（MCS）患者的室内环境质量、免疫状态和对嗅觉刺激的反应。MCS患者生活在非常干净的室内环境空间中。MCS的免疫状态不是Th2优势的，与变态反应不同。MCS患者的前额叶皮层（PFC）区域被嗅觉刺激激活。PFC对恶臭物质的过度反应、免疫系统的特异性变化是MCS的特征。

We investigated indoor environmental quality, immunological status, and response to olfactory stimulus regarding patients with Multiple Chemical Sensitivity (MCS) in Hyakumanben clinic “Sick house outpatient”. MCS patients lived at very clean indoor environmental spaces in their houses. The immunological status of MCS is not Th2 dominant and different from allergy. Prefrontal cortex (PFC) area of MCS patients activated by olfactory stimuli. The excess responses of PFC to odorous substances, specific changes of immune system were indicated as characteristics of MCS.