Elucidation of the biological properties of triple negative breast cancer and construction of a therapeutic strategy

三阴性乳腺癌组织学分级高，血管浸润进一步，高血管化和增殖潜力。我们的研究结果表明，三阴性乳腺癌可以进一步细分为三个不同的组（低，中，高）根据风险评分系统评估以下五个预后变量（病理肿瘤大小，病理淋巴结状态，基底样类型，Ki67标记指数和微血管密度）。三组间生存率差异有统计学意义。总之，这种分类是有用的治疗决策工具，为三阴性患者。

Triple negative breast cancer observed high histological grade, further vascular invasion, high vascularization and proliferation potential. Results of our study demonstrated that triple negative breast cancer could be further sub-classified into three different groups (low, intermediate, high) according to the Risk Score System evaluating the following five prognostic variable (pathological tumor size, pathological node status, basal-like type, Ki67 labeling index and Microvessel Density). Difference was observed in the survival rate significantly in these three groups. In conclusion, this classification is useful as a therapeutic decision-making tool for triple negativepatients.