Regulation mechanism of antigen recognition by controlling the interaction of dendritic cells and mucosal cells in the epithelium
Regulation mechanism of antigen recognition by controlling the interaction of dendritic cells and mucosal cells in the epithelium
批准号:
22791615
负责人:
KUROSE Makoto
金额:
$2.58万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
鼻咽部和鼻黏膜位于宿主防御外来病原体的前沿,在获得性免疫和先天免疫中起着重要作用。为了阐明过敏感染的免疫系统,我们分析了人鼻咽上皮上皮的上皮屏障功能和抗原递呈机制。此外,我们还对树突状细胞与粘膜上皮的相互作用进行了研究。
英文摘要
Nasopharynx and nasal mucosa are located at the forefront of the host defense against foreign pathogens, which plays an important role in acquired immunity and innate immunity. To elucidate the immune system of allergy infection, we analyzed the mechanism of epithelial barrier function and antigen presentation in the nasal epithelium of human nasopharyngeal epithelium. In addition, we made a research on the interaction of dendritic cells and mucosal epithelium.
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会议论文
Regulation mechanism of antigen recognition by the interaction control of M cells and intraepithelial dendritic cells and mucosal epithelium
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批准号:24791794
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2012
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负责人:KUROSE Makoto
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依托单位:
海外基金