Fabrication of high-efficient 2-photon fluorescent materials for bio- applications using metal-particle/dye-aggregate composites

建立了稳定水介质中染料聚集体的方法。与溶解的染料相比，聚集体将双光子激发荧光的效率提高了100倍。并提出了在颗粒表面形成金壳的方法。由于壳层诱导的激发强度增强，吸附在壳层上的聚集体的效率比没有壳层的颗粒高3倍。因此，染料聚集和金壳的结合获得了比溶解染料高出100倍的效率。

The method to stabilize dye-aggregates in aqueous media was developed. The aggregates enhanced the efficiency of the 2-photon excited fluorescence by up to 100 times compared to the solubilized dyes. The method to form a gold-shell on particle was also developed. Due to the enhancement of the excitation intensity induced by the shell, the aggregates adsorbed on the shell exhibited 3 times higher efficiency than those on the particle without the shell. Thus, the combination of dye-aggregation and the gold shell achieved several 100-fold higher efficiency compared to the solubilized dyes.