Challenge for Fabrication of Medical Devices using Next Generation' s Ti Alloy Powders by Laser Forming

在优化激光成形工艺参数的基础上，制备了不同尺寸蜂窝孔的Ti-6Al-7 Nb蜂窝结构抗压试件。孔径为600μm的蜂窝状结构的压缩强度为68-302 MPa，2.密度为18 g/cm^3。这些值大致等于人股骨的压缩强度21-170 MPa和2。00 g/cm^3。在为生物相容性培养成骨细胞的情况下，在培养的早期阶段，细胞以六边形形状定向，并且在21天后，观察到细胞生长到六边形形状的孔中。此外，在较小的蜂窝孔径（300μm）下，整个蜂窝区域都形成了网状结构。这意味着较小的蜂窝孔尺寸促进细胞向蜂窝孔中生长，换句话说，激光成形技术可能非常可靠地制造生物医学器件。

Honeycomb structured compression strength specimens(Ti-6Al-7Nb) which have various honeycomb hole sizes were fabricated in optimizing the process parameters of laser forming. The honeycomb structure with hole diameter of 600μm showed 68-302 MPa in compression strength and 2. 18 g/cm^3 in density. Those values are approximately equal to that of human femur which has 21-170 MPa in compression strength and 2. 00 g/cm^3 in density. In the case of osteobalsts culturing for biocompitability, the cells were oriented in hexagonal shape at the early stage of culturing, and after 21 days the cells growing into the hexagonal shaped holes were observed. In addition, in smaller honeycomb hole size(300μm), network cell growth was formed over the entire area. This means that smaller honeycomb hole size promotes the cell growing into the honeycomb hole, in another word, the laser forming technique might be very reliable to fabricate bio-medical devices.