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Development of new treatments of chemotherapy-induced peripheral neuropathy

Development of new treatments of chemotherapy-induced peripheral neuropathy
化疗引起的周围神经病变新疗法的开发
批准号:
22659285
负责人:
KAWAMATA Tomoyuki
金额:
$2.04万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

项目摘要

项目成果

KAWAMATA Tomoyuki的其他基金

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相关文献

中文摘要
翻译
紫杉醇治疗通常与剂量限制性疼痛性周围神经病变和随后的神经性疼痛相关,这些疼痛对标准镇痛药有抗性。我们的研究结果表明,DRG中卫星细胞来源的l-丝氨酸在紫杉醇诱导的疼痛性周围神经病变中起重要作用。这些发现可能会导致治疗紫杉醇引起的疼痛周围神经病变的新策略。
英文摘要
Paclitaxel treatment is often associated with dose-limiting painful peripheral neuropathy and subsequent neuropathic pain that is resistant to standard analgesics. Our results showed that satellite cell-derived L-serine in the DRG plays an important role in paclitaxel-induced painful peripheral neuropathy. These findings may lead to novel strategies for the treatment of paclitaxel-induced painful peripheral neuropathy.
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会议论文
Molecular signaling of pruritus induced by endothelin-1 in mice
内皮素-1诱导小鼠瘙痒的分子信号传导
DOI: 10.1258/ebm.2010.010121
发表时间: 2010-11-01
期刊: EXPERIMENTAL BIOLOGY AND MEDICINE
影响因子: 3.2
作者: [Liang, Jiexian, Kawamata, Tomoyuki, Ji, Wenjin]
通讯作者: Ji, Wenjin
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Koizuka S, Saito S, Tobe M, Sekimoto K, Obata H and KoyamaY, 肥塚史郎, 田中秀典]
通讯作者: 田中秀典
Spinal NMDA Receptor Is Involved in Bone Cancer-Induced Ongoing Pain but Not Movement-Evoked Pain
脊髓 NMDA 受体与骨癌引起的持续疼痛有关,但与运动诱发的疼痛无关
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kawamata T, Fuseya S, Furuse S, Yamamoto K, Kawamata M]
通讯作者: Kawamata M
悪心・嘔吐.支持・緩和薬物療法マスターがん治療の副作用対策.江口研二,相羽恵介,門田和気,高野利実編
恶心和呕吐。针对癌症治疗副作用的支持性和姑息性药物治疗大师,作者:Kenji Eguchi、Keisuke Aiba、Wake Kadota 和 Toshimi Takano。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Kawamata T, Fuseya S, Furuse S, Yamamoto K, Kawamata M, 川股知之, 川股知之]
通讯作者: 川股知之
共 36 条
    Development of novel therapies for itch by a positive charged lidocaine
    • 批准号:
      24659693
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2012
    • 负责人:
      KAWAMATA Tomoyuki
    • 依托单位:
    Development of novel therapies for cancer pain based on supraspinal mechanisms
    • 批准号:
      23390374
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.81万
    • 财政年份:
      2011
    • 负责人:
      KAWAMATA Tomoyuki
    • 依托单位:
    Mechanisms of endogenous cannabinoid receptor activation-induced analgesia and its application to intractable cancer pain
    • 批准号:
      19390407
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.15万
    • 财政年份:
      2007
    • 负责人:
      KAWAMATA Tomoyuki
    • 依托单位:
    Involvement of TRPV1 in bone cancer pain : development of novel strategies for treating cancer pain
    • 批准号:
      17591646
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.18万
    • 财政年份:
      2005
    • 负责人:
      KAWAMATA Tomoyuki
    • 依托单位:
    海外基金