Clarify the mechanism of attenuating effect at muscle fatigue by carnosine ingestion.

肌肽作为一种具有潜在的缓解肌肉疲劳作用的补品，近年来受到国内外的广泛关注。本研究的目的是阐明肌肽摄入对肌肉疲劳的减弱作用机制，特别是在等长膝关节伸展运动中，高强度运动和肌肉能量代谢时发生的肌浆网（SR）功能。综上所述，肌肽对肌肉疲劳的缓解作用参与了改善SR功能和抑制细胞内pH的降解。

In recent year, Carnosine attract at home and abroad attention as supplement with potential attenuating effect at muscle fatigue. The purpose of this study was clarified the mechanism of attenuating effect at muscle fatigue by carnosine ingestion, in particular, sarcoplasmic reticulum(SR) function that occur with high-intensity exercise and muscle energy metabolism during isometric knee extension exercise. In the results, attenuating effect at muscle fatigue by carnosine ingestion were participate in improvement of SR function and inhibiting the degradation of intracellular pH.