Development of function and elucidation of mechanism on the skin by oral conjugated linolenic acid

本研究旨在探讨口服共轭亚麻酸对皮肤褶积的抑制作用。以-亚麻酸为原料，采用碱异构化法制备共轭亚麻酸。大鼠自由给予共轭亚麻酸4周。测定皮肤脂质（总脂、甘油三酯、总胆固醇、游离脂肪酸和游离胆固醇）。因此，在本研究中，口服共轭亚麻酸对皮肤的抗肥胖作用没有显著的发现。

The aim of the present study was to examine the inhibiting function of skinfold accumulation by oral conjugated linolenic acid. The conjugated linolenic acid was made from gamma-linolenic acid with the method of alkali-isorization. Rats were freely given conjugated linolenic acid for four weeks. Skin lipids(total lipid, triacylglycerol, total cholesterol, free fatty acid and free cholesterol) were determined. As a result, anti-obesity of the skin by oral conjugated linolenic acid in this study were not remarkably found.