Therapeutic effect of repetitive transcranial magnetic stimulation in chronic aphasia patients and brain activation patterns

我们应用抑制性重复经颅磁刺激（rTMS），以右半球布罗卡的同源物，每天10天的慢性失语症患者。描述性观察证实失语症有改善，但标准语言测试结果显示rTMS治疗后失语症无明显改善。近红外光谱成像测得的偏侧性指数显示大多数患者在图片命名任务中表现为右脑优势激活。rTMS治疗前后侧化指数的变化趋势不一致。

We applied inhibitory repetitive transcranial magnetic stimulation (rTMS) to right-hemisphere Broca's homologue daily, for 10 days in chronic aphasia patients. Although improvement of aphasia was admitted in a descriptive observation, standard language test showed no significant improvement after rTMS treatments, Laterality index, which obtained by near-infrared spectroscopic mapping, revealed most patients demonstrate right dominance brain activation during picture naming task. Then, change in laterality index before and after rTMS treatments did not show uniform trend.