Effect of difference in the environment on the reduction of risks caused by pharmaceuticals and antibiotic-resistance

考虑到与间接使用处理过的废水有关的风险，研究了水环境中药物和耐抗生素细菌的命运。硝化作用促进了一组药物的降解。从富营养化环境中获得的硝化菌对抗生素的敏感性一般低于从原始环境中获得的硝化菌。铜绿微囊藻对氟喹诺酮类抗菌素极为敏感。对第三代头孢菌素耐药的大肠埃希菌比例在3.1% ~ 4.5%之间。对氟喹诺酮类药物和第三代头孢菌素多重耐药的大肠杆菌比例随河流流向而增加。

The fate of pharmaceuticals and antibiotic-resistant bacteria in the water environments was investigated considering the risks related with indirect use of treated wastewater. Nitrification promoted the degradation of a group of pharmaceuticals. The nitrifiers obtained from the nitrient-rich environments were generally less sensitive to the antibiotics than those obtained from the pristine environments. Microcystis aeruginosa was extremely sensitive to fluoroquinolone antimicrobials. The ratios of Escherichia coli resistant to third-generation cephalosporins were in the range of 3.1% - 4.5% in the case of the samples taken from the Tama river. The ratios of multiple-resistant E. coli to both fluoroquinolones and third-generation cephalosporins were increased along with flow direction in the river.