Basic dosimetry study for microbeam radiation therapy

这项研究的目的是评估同步辐射设施Spring8的X射线微束剂量学。我们将重点放在非均匀体模几何结构的剂量测量上。利用带有CCD摄像机的显微镜测量了多缝微束X射线辐照下GaF-铬薄膜的光学密度分布。非均匀体模中的峰谷剂量率随体模密度的不同而不同。这一结果表明，在微束放射治疗的生物学效应评估中，微束剂量学是必要的。

The aim of this study is to evaluate a X-ray microbeam dosimetry at the synchrotron radiation facilities SPring-8. We have focused on the dose measurements in inhomogeneous phantom geometries. The microscope with CCD camera was used to measure the optical-density distribution of GafChromic films irradiated with multi-slit microbeam X-rays. The peak and valley dose rates in inhomogeneous phantom geometries were found to differ according to density variation in phantom. This result suggests that the microbeam dosimetry is required with evaluation of biological effects in microbeam radiation therapy.