A research on the optimal protocol for cryoablation of endocrine organ including adrenal gland and thyroid gland

肾上腺冷冻消融在解冻过程中引起高血压危象。这种高血压危象是由高血浆儿茶酚胺引起的，并迅速观察到。我们的结论是，血压监测和控制应采用动脉血压和动脉输注α受体阻滞剂。冷冻消融甲状腺显示，冰球的面积明显小于肝或肾。每次实验中，冰球的大小都是不同的。这种冰球大小的差异是由包括颈总动脉或静脉在内的区域血管的“热沉效应”引起的。

Cryoablation of the adrenal gland caused a hypertensive crisis during thawing. This hypertensive crisis was conducted by high plasma catecholamines and was observed rapidly. We concluded that the blood pressure should be monitored and controlled using arterial blood pressure and arterial infusion of alpha-blocker.Cryoablation of the thyroid gland revealed that the area of the ice ball was significantly smaller than that of liver or kidney. The size of the ice ball was different in each experiments. This difference in the size of the ice ball was caused by "heat sink effect" by a regional vessels including common carotid artery or vein.