Evaluation for bone quality in jaw bone using biochemical markers of bone turnover

骨质疏松症是种植体治疗中的一个危险因素，其特征不仅在于骨矿物质密度降低，还在于骨质量降低。 骨转换的生化指标是一种有用的诊断方法，用于一般的骨质量。本研究旨在探讨骨转换生化指标与颌骨局部骨质量及种植体周围牙槽骨丢失的相关性。骨吸收标志物NTX与骨结构参数呈负相关（r=-0.43 ~-0.58），与骨吸收标志物DPD呈正相关（r=0.32 ~ 0.41）。这些结果表明，生化指标是评价下颌骨质量和预测种植治疗风险的有用方法。

Osteoporosis known as a risk factor in implant treatment is not only characterized by a decrease in bone mineral density but also a reduction in bone quality. Biochemical markers of bone turnover are useful diagnostic procedure for general bone quality. The aim of this study is to investigate the correlation between biochemical markers of bone turnover and local bone quality of jaw bone and peri-implant crestal bone loss. NTX as bone resorption marker had negative correlation with skeletal structural parameters (r=-0.43 to -0.58), and positive correlation with DPD as bone resorption marker and peri-implant crestal bone loss after 12 months implant placement was recognized (r=0.32 to 0.41) in postmenopausal women. These results suggest, biochemical makers are useful methods to evaluate bone quality of mandibular and to predict a risk for implant treatment.