Synthesis of Polymer Membranes with Hierarchically Arrayed ChiralNanopores and Development of Supersmart Separation Ability

合成了类似于DNA或酶等生物大分子的有规立构的单手螺旋人工聚合物，并通过浇铸聚合物溶液形成了由有规立构的单手螺旋聚合物组成的自支撑膜。通过去除沿着主链分级排列的手性取代基，可以合成具有源自手性取代基的手性信息的纳米孔印迹的自支撑膜。所获得的具有手性印迹纳米孔的膜显示出光学拆分能力，这是有希望的应用于药物开发。

Stereoregular one-handed helical artificial polymers similar to biopolymers such as DNA or enzymes were synthesized and could formed self-supporting membranescomposed of the regular one-handed helical polymers by casting of the polymer solution. By removing of chiral substituents hierarchically arranged along the main chain, self-supporting membranes having nano-pores imprinting of chiral information originated from the chiral substituents could be synthesized. The obtained membrane having chiral imprinted nano-pores showed a optical resolutionability which is promising to application for drug development.