analysis of transposable genes in the tumors of hypersensitive individuals

基因组不稳定性是肿瘤发生发展的重要调控机制之一。染色体分离和中心体扩增的调节被认为与基因组的不稳定性有关。可转座基因“反转录转座子”也与此有关。在这项研究中，虽然我们使用了比以前更快、更高通量的技术，但我们没有找到肿瘤特异性的长散布元件-1(LINE-1，L1)。

Genomic instability is one of the important regulatory mechanisms in the tumor development. The regulations of chromosome segregation and centrosome amplification are known to be involved in the genomic instability. Transposable genes “retrotransposons” are also implicated in it. In this study, although we used the more faster and high throughput technique compared with previous one, we could not find the tumor specific long interspersed element-1 (LINE-1, L1).