A study on the association between urinary aluminum concentration and pre-clinical findings among aluminum handling and non-handling workers

为了评价铝对人体的毒性，我们测定了接铝工人和不接铝工人的尿铝浓度，并探讨了尿铝浓度与临床前结果的关系。铝搬运工人尿铝浓度范围为5.4~55.1微克/克铬，非搬运工人尿铝浓度为5.6~15.6微克/克铬。它们之间存在着显著的差异。两组的临床前表现无显著差异。虽然铝加工工人的尿铝排泄量增加，但已证明铝对人体无害，至少在尿铝低于55ug/g铬的情况下是如此。

In order to estimate the toxicity of aluminum to humans, we measure the aluminum concentration in urine among the aluminum handling and non-handling workers and investigate the relationships between the urinary aluminum concentration and the pre-clinical findings. The aluminum concentration in urine ranges from 5.4-55.1ug/g cre in the aluminum handling workers and the aluminum concentration in urine ranges from 5.6-15.6ug/g cre in the non-handling workers. There are significant differences between them. There are no significant differences in the pre-clinical findings. Although the excretion of aluminum in urine increases in aluminun handling workers, it is demonstrated that aluminum is not harmful to humans, at least in case that aluminum in urine is below 55ug/g cre.