Study on canine periodontal disease as zoonosis

本研究的目的是确定犬牙周病是否为人畜共患病，并阐明牙周病与全身性疾病的关系。口腔拭子样本是从作为家庭宠物饲养的狗身上收集的。聚合酶链式反应被用来检测牙周病细菌株的存在-10株来自人，1株来自狗。在被分析的100只或更多的狗中，几乎所有的狗都检测到了古拉氏肺孢子虫。通过对菌毛基因(FIMA)序列的分析，我们鉴定出3种类型：A型、B型和C型。C型毒力最强。通过研究牙周和全身疾病之间的关系，发现古氏肺孢子虫C型与心血管疾病之间存在相关性。

The objective of the present study was to determine whether dog periodontal diseases are zoonotic and clarified the relationship between periodontal and systemic diseases. Oral swab samples were collected from dogs kept as family pets. Polymerase chain reaction was used to detect the presence of periodontopathic bacterial strains—10 from humans and 1 from dogs. P. gulae was detected in nearly all of the 100 or more dogs that were analyzed. By analyzing a fimbrial gene (fimA) sequence, we identified 3 types of P. gulae: type-A, type-B, and type-C. Type-C was the most virulent. A correlation between P. gulae type-C and cardiovascular disease was found by investigating the association between periodontal and systemic diseases.