Beneficial effect of hybrid training of voluntary and electrical muscle contractions on elderly subjects with non-alcoholic fatty liver diseases and the construction of nursing intervention model

与肥胖相关的肝功能障碍的主要原因被认为是非酒精性脂肪性肝病（NAFLD）。NAFLD是一种慢性疾病，在某些情况下可发展为非酒精性脂肪性肝炎（NASH）和肝硬化。除了饮食和运动疗法外，目前还没有有效的治疗NAFLD的方法。为了防止长时间呆在空间站的宇航员肌肉萎缩，开发了自愿肌肉收缩和电性肌肉收缩的混合训练。在这项研究中，我们旨在将混合训练作为一种运动疗法应用于NAFLD患者。训练持续了6个月。结果显示，老年NAFLD患者下肢混合训练具有抗肥胖作用，改善肝功能障碍和胰岛素抵抗，并增加肌肉力量和减少异位脂肪。

The main cause of hepatic function disorders associated with obesity is considered to be non-alcoholic fatty liver disease (NAFLD). NAFLD develops because of lipid accumulation in the liver, and it is a chronic disease that can, in some cases, progress to non-alcoholic steatohepatitis (NASH) and liver cirrhosis. Other than dietary and exercise therapies, no effective treatment method for NAFLD has been established. Hybrid training of voluntary and electrical muscle contractions was developed to prevent muscle atrophy in astronauts spending long periods in space stations. In this study, we aimed to apply hybrid training as a form of exercise therapy for NAFLD patients. The training was continued for 6 months. The results revealed that hybrid training for the lower extremities in elderly subjects with NAFLD exerts an anti-obese effect as well as improves liver dysfunction and insulin resistance in association with an increase in the muscle strength and a decrease in the ectopic fat.