Effectiveness and mechanisms of exercise with blood flow restriction aimed at preventing muscle atrophy in diabetes.

这项研究表明，离心收缩会导致II型糖尿病患者骨骼肌明显损伤。此外，下坡跑训练减轻机械应力的II型糖尿病骨骼肌。因此，在本研究中，通过运动方案抑制糖尿病骨骼肌的脆性，旨在维持骨骼肌质量。此外，本研究还探讨了不同水平的血流限制对离心收缩的影响。因此，存在血流限制诱导骨骼肌损伤的阈值。基于这些发现，需要进一步的研究来检查运动训练与血流限制在II型糖尿病中的作用。

This study indicated that the eccentric contraction induced marked skeletal muscle damage in type II diabetes. Moreover, downhill running training alleviated mechanical stress to type II diabetic skeletal muscle. Thus, fragility of diabetic skeletal muscle was inhibited by exercise protocol in present study aimed to maintain skeletal muscle mass. In addition, this study examined effects of eccentric contraction with differential level of blood flow restriction. As a result, there exists a threshold where blood flow restriction induces skeletal muscle damage. Based on these findings, further studies are required to examine the effects of exercise training with blood flow restriction in type II diabetes.