Common bean extract intake improves lipid/carbohydratemetabolism disorder

摄入普通豆提取物可抑制高脂诱导的体重增加、肝脏和脂肪组织的体重增加，血清脂肪/碳水化合物参数和脂肪细胞因子浓度也接近正常小鼠。此外，摄入普通豆提取物可减少肝脏中的脂滴积聚。这些改善作用的机制可能与调节脂糖代谢途径的基因表达有关，也可能与调节多种转录因子和信号因子的激活有关。

High fat-induced body weight gain, liver and adipose tissue weight gain were suppressed by ingestion of common bean extract, and serum fat/carbohydrate parameters and adipocytokines concentration were also improved near by normal mice. Moreover, lipid droplet accumulation in the liver was reduced by ingestion of common bean extract. It is suggested that the mechanisms of these improvement effects may be regulated the gene expression of lipid-carbohydrate metabolism pathways and also be regulated the activation of the multiple transcriptional factors and signaling factors.