Phylogenomics of Spiralia: Syndermata, Gnathifera and the Platyzoa hypothesis

Nemathelminthes和Gnathifera，历史上被合并为Aschelminthes，包括基本不同的蠕虫状生物，它们被归为许多不同的动物门。这些门的系统发育关系是有争议的，涉及到“腔虫”和“外生虫”的争论。类似蠕虫的异涡虫是另一个神秘的分类单元，它可能代表了一个新的后口动物谱系。在深层后生动物系统发育优先项目的框架内，我们建议对一种线虫、一种棘头虫和异种涡虫分别进行4000次EST读取。这些数据将用于重建后生动物树的“深层”分支，并选择基因，这些基因可用于解决门内有争议的关系。-在对无害环境技术数据进行生物信息学分析时，将与其他基因组模式生物进行比较，研究这三个分类群的基因编码区域和基因库的基本特征。这有望改善我们对基本的后生动物基因含量和从无脊椎动物到脊椎动物基因组的进化转变的看法。此外，我们将关注无脊椎动物珠蛋白基因的进化，以及最近发现的新型脊椎动物珠蛋白。

Nemathelminthes and Gnathifera, historically joined as Aschelminthes, comprise fundamentally diverse worm-like organisms, which have been grouped into a number of distinct animal phyla. The phylogenetic affiliations of these phyla are controversial, being involved in the `Coelomata` and `Ecdysozoa` debates. The worm-like Xenoturbella is another enigmatic taxon, which may represent a novel deuterostome lineage. Within the framework of the priority project Deep Metazoan Phylogeny , we propose to initially gene rate 4000 EST reads each for one nematomorph species, one acanthocephalan and for Xenoturbella. These data will be used to reconstruct `deep` branches of the metazoan tree and to select genes, which can be employed to resolve controversial relationships within the phyla. - In a bioinformatical analysis of the EST data, the basic features of the gene coding regions and the gene repertoire of the three taxa will be studied in comparison with other genomic model organisms. This promises to improve our view of the basic metazoan gene content and the evolutionary transition from invertebrate to vertebrate genomes. Additionally, we will focus on the evolution of invertebrate globin genes with regard to recently discovered, novel vertebrate globins.