SFB 416: Chemische und biologische Synthese und Transformation von Naturstoffen und Naturstoff-Analoga

合作研究中心416的目标是重要的生物活性天然产物及其类似物的化学和生物合成和转化。为此目的，将开发和应用高效和选择性的合成方法。重点是催化程序的使用。此外，大自然的酶潜力--无论是直接的还是在基因技术变异之后的--都将得到开发。该项目的一个组成部分是对所制备化合物的生物活性进行调查，并澄清其作用方式。合作研究中心416一方面将通过开发新的化学和生化方法，为一些重要和有趣的天然产物及其类似物提供更好的机会，另一方面有助于更深入地了解生物系统的重要相互作用。

The aim of the collaborative research centre 416 is the chemical and biological synthesis and transformation of important bioactive natural products and their analogues. For this purpose, highly efficient and selective synthetic methods will be developed and employed. A point of emphasis is the use of catalytic procedures. In addition, the enzymatic potential of Nature - either directly or after gene technical variation - will be exploited. An integral part of the project is the investigation of the biological activity of the prepared compounds and a clarification of their mode of action. The collaborative research centre 416 shall provide a better access to some important and interesting natural products and their analogues by developing new chemical and biochemical methods on the one hand, and on the other hand contribute to a deeper understanding of important interactions of biological systems.