Understanding nutritional interactions for targeted microbiome manipulation

该项目旨在确定如何有效地操纵微生物群落，使其造福于宿主。微生物组操作一直是聚光灯下的一个潜在解决方案，可以维持或改善几个宿主的健康，从受威胁的珊瑚物种到牲畜和人类，但工业规模战略的发展一直很缓慢。该项目建议绘制微生物之间的营养相互作用图，并确定微生物组操作的级联效应。这将产生关于群落稳定性和延展性的生物过程的基本知识，这最终将有助于设计优化的微生物群。

This project aims to identify how microbial communities, known as microbiomes, can be effectively manipulated to the benefit of their host. Microbiome manipulation has been in the spotlight as a potential solution to maintain or improve the health of several hosts, from threatened coral species to livestock and humans, but the development of industry-scale strategies has been slow. This project proposes to chart the nutritional interactions among microorganisms and to identify cascade effects of microbiome manipulation. This will generate fundamental knowledge on the biological processes underlying community stability and malleability, which will ultimately help engineering optimised microbiomes.