Interaction of light with tissues: A hyper-spectral approach

该项目旨在解决包括皮肤和软骨在内的组织的非接触评估的一个重要问题。通过使用极宽的光谱--在太赫兹和近红外之间--将探索由于组织性质从宏观到纳米尺度的变化而引起的散射和吸收的影响。通过将光谱学与新型太赫兹和中红外扫描近场光学显微镜相结合，将在模型和实验中解决组织特性的空间变化。这些结果将促进对光与多层组织相互作用的基本理解。这将为推进生物工程研究、太赫兹技术和生物医学设备的开发提供工具。

This project aims to address an important problem of noncontact assessment of tissue including skin and cartilage. By using extremely wide spectrum – between the terahertz and the near infrared – the effects of scattering and absorption arising from the variation of tissue properties from macro- to nano-scale will be explored. Spatial variations of tissue properties will be addressed in model and experiment by combining spectroscopy with the novel terahertz and mid-infrared Scanning Near field Optical Microscopy. The outcomes will advance fundamental understanding of light interaction with multi-layered tissues. This will provide a tool for advancing bioengineering research, terahertz technology, and development in biomedical devices.