Secure Homomorphically Encrypted National Registry of COVID-19 Recovered Plasma Donors
Secure Homomorphically Encrypted National Registry of COVID-19 Recovered Plasma Donors
批准号:
10164918
负责人:
Aziz A Boxwala
金额:
$22.07万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-09-24 至 2021-08-31
关键词:
AcuteAlgorithmsAntibodiesBloodCOVID-19COVID-19 pandemicCOVID-19 vaccineCase SeriesClinical InformaticsCodeCollaborationsCommunicable DiseasesCompanionsComputer softwareConsentCritical IllnessCustomDataData AnalysesDiseaseDockingEbolaEnrollmentFDA approvedFaceGeneticGoalsGrantHealthHospitalsIndividualInformed ConsentInstitutionInternetLicensingMachine LearningMethodsMiddle East Respiratory SyndromeModelingOwnershipParentsPatientsPhysiciansPlasmaPositioning AttributePrivacyPrivatizationProcessProtocols documentationRecording of previous eventsRegistriesResearch PersonnelResourcesSecureSecuritySevere Acute Respiratory SyndromeSpanish fluStigmatizationSurvivorsSystemTeaching HospitalsTimeUnited StatesUnited States National Institutes of HealthViral Load resultbaseblood groupcomputer human interactioncytokinedata centersdata privacydata sharingdesigndigitaleffective therapyencryptiongenomic datahealth care service organizationimprovedindustry partnerinnovationnovelpandemic diseaseparent grantparent projectpatient privacyprivacy protectionprocess optimizationprogramsscreeningsmartphone Applicationweb site
中文摘要
项目摘要
FDA最近批准用恢复期血浆(CP)治疗10岁以下的重病患者,
新冠肺炎。有很多机构和医院已经实施了CP计划,但他们都面临着
找到足够和合适的捐助者的挑战。配套的制约,供给的不平衡
需求和隐私方面的问题对捐助者的参与提出了若干挑战。考虑多个
利益相关者(患者,捐赠者,医院),我们将开发基于多密钥同态的新算法
加密以保护患者和捐赠者的隐私,并具有简化注册的附加功能
流程,并对(从COVID-19中康复的患者的)血浆捐献进行优化。我们
致力于公益,并将免费提供代码/资源内开发的
这个项目的框架。如果我们成功了,我们的项目将为潜在的血浆建立一个安全的国家登记处。
捐赠者,并可能挽救许多生命。
英文摘要
PROJECT SUMMARY
Treatment with convalescent plasma (CP) was recently approved by the FDA for seriously ill patients of
COVID-19. There are many institutions and hospitals that have implemented CP programs, but they all face
the challenge of finding sufficient and appropriate donors. The constraints of matching, imbalances in supply
and demand, and privacy concerns pose several challenges to engage donors. Considering multiple
stakeholders (patients, donors, hospitals), we will develop new algorithms based on multikey homomorphic
encryption to protect the privacy of patients and donors, with additional functionality to simplify the registration
process, and conduct optimization for plasma donation (of patients who recovered from COVID-19). We are
dedicated to the public good and will make freely available the code / resources developed within the
framework of this project. If we succeed, our project will build a secure national registry for potential plasma
donors and may save many lives.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.jbi.2020.103602
发表时间:
2020-12
期刊:
Journal of biomedical informatics
影响因子:
4.5
作者:
[Karimi S, Jiang X, Dolin RH, Kim M, Boxwala A]
通讯作者:
Boxwala A
Secure outsourced computation of genomic data
-
批准号:9906292
-
项目类别:
-
资助金额:$34.49万
-
财政年份:2019
-
负责人:Aziz A Boxwala
-
依托单位:
Reliable Performance of Cancer Screening using a Computer-based Monitoring System
-
批准号:7481710
-
项目类别:
-
资助金额:$12.25万
-
财政年份:2008
-
负责人:Aziz A Boxwala
-
依托单位:
CREATING GUIDELINES THAT ADAPT TO LOCAL CONTEXTS
-
批准号:6627573
-
项目类别:
-
资助金额:$23.9万
-
财政年份:2001
-
负责人:Aziz A Boxwala
-
依托单位:
海外基金