OxDX: Machine learning enhanced point of care diagnosis platform for infectious diseases: faster, more accessible, user intuitive, leveraging novel fluorescent labelling of enveloped viruses.

总部位于英国的初创企业OxDX Ltd将通过开发传染病诊断平台，利用OxDX独特的病原体识别技术，改变现有的人类病毒检测方法。由流感、副流感和呼吸道合胞病毒等病原体引起的传染病每年导致数千人死亡。目前的检测工作流程严重依赖中央实验室，检测能力和物流网络在需求高峰时举步维艰。目前用于病毒检测的诊断方法，如病毒培养、RT-PCR或基于抗原的快速诊断测试，往往因等待时间长或灵敏度和特异性有限而受到阻碍。因此，迫切需要分散检测解决方案，将检测从实验室转移到提供直接、快速和敏感病毒检测方法的护理点。该项目专注于OxDX诊断平台的开发，提供成本降低的阶段性变化，并在护理点提供实验室质量结果。该平台适合临床以外的非临床专家使用，可以快速部署，提高全球超快、准确的传染病诊断的可及性。

UK-based start-up OxDX Ltd will transform existing approaches to human virus detection, through the development of an infectious disease diagnosis platform, leveraging OxDX's unique pathogen identification technology.Infectious diseases caused by pathogens like influenza, parainfluenza and respiratory syncytial virus cause many thousands of deaths annually. Current testing workflows rely heavily on centralised laboratories, with testing capacity and logistics networks struggling during peak demand spikes.Current diagnostic approaches for virus detection, such as virus culture, RT-PCR or antigen-based rapid diagnostic tests, are often hampered by long waiting times or limited sensitivity and specificity. As a result, there is an urgent need for decentralising testing solutions, moving testing away from laboratories to the point of care that provides straightforward, fast and sensitive viral detection methods.This project focuses on the development of OxDX's diagnostic platform, providing a step-change in cost reduction and delivering laboratory quality results at the point of care.Suitable for utilisation by non-clinical experts beyond clinical settings, the platform can be rapidly deployed, improving global accessibility to ultra-fast, accurate infectious disease diagnostics.