Neurology Physician Research Training Grant

医生科学家在将基础科学发现转化为新的临床研究方面占据着关键地位。 治疗。在神经病学领域，医生科学家一直处于最前沿， 例如，开发人类疾病的新模型，开发帕金森氏症的新临床治疗方法， 疾病，癫痫和中风，并确定脑肿瘤，神经胶质祖细胞和 神经干细胞可能促进新的疗法。然而，医生的相对和绝对数量 在过去的25年里，尽管NIH的研究预算翻了一番，但科学家的数量一直在下降。 这个时代的一部分。这在很大程度上是由于长期性质的培训，为一个医生，科学家。 美国国立卫生研究院已经认识到这个问题，在这个RFA的研究教育计划， 神经病学、神经外科、神经病理学、神经放射学和急诊学的住院医师和研究员 药神经病学研究教育计划的目标在这个拨款建议是训练神经病学 住院医师通过直接的调查研究，口头和书面的基础或临床科学研究 科学的演示和密集的指导职业发展。培训计划的结构 结合了几个层次的指导和集中时间的口头和书面陈述，与高潮 在职业发展补助金的生产。这项培训计划得到了一个优秀的 在加州大学洛杉矶分校神经学系的神经科学研究和教育的环境。部 一直是美国国立卫生研究院资助的神经内科前十名，并拥有大量的临床和基础研究 教师与多样化和资金充足的方案。居住计划相对较大（每年9人）， 灵活地将选定的居民纳入研究计划，并有培训许多 学术神经学家拟议的教育计划利用了大量的神经科学 在神经科和相关部门的社区有一个大的和科学的 具有丰富研究和培训经验的多元化导师团队。通过服务于整合 临床和基础神经科学家与神经病学居民在他们的临床培训的背景下 计划，该补助金开发了一个转化神经科学培训补助金。

Physician-scientists occupy a critical niche in the translation of basic science findings into new clinical treatments. Within the field of neurology, physician-scientists have been at the forefront, among many examples, in developing new models of human disease, developing new clinical treatments for Parkinson’s disease, epilepsy and stroke and identifying novel genetic signatures of brain tumors, glial progenitors and neural stem cells that may facilitate new therapies. However, the relative and absolute numbers of physician scientists have been declining over the past 25 years, despite the doubling of the NIH research budget during a portion of this epoch. This is in large part due to the prolonged nature of the training for a physician-scientist. The NIH has recognized this problem in the release of this RFA for Research Education Programs for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, Neuroradiology and Emergency Medicine. The goal of the neurology research education program in this grant proposal is to train neurology residents in either basic or clinical science research through direct investigative study, oral and written scientific presentation and intensive mentored career development. The structure of the training program incorporates several tiers of mentoring and focused time on oral and written presentations, with a culmination in the production of career development grant. This training program is supported by an excellent environment for neuroscience research and education in the UCLA Neurology Department. The department has been a top ten NIH funded neurology department, and has a large clinical and basic research faculty with diverse and well-funded programs. The residency program is relatively large (9 per year) with flexibility to place selected residents in a research program, and has a track record of training many academic neurologists. The proposed education program takes advantage of the substantial neuroscience community within the Neurology Department and allied departments to have a large and scientifically diverse group of mentors with great depth of research and past training experience. By serving to integrate clinical and basic neuroscientists with Neurology residents in the context of their clinical training program, this grant develops a Translational Neuroscience Training Grant.