Electrochemical Oxygen Concentrator

项目总结 氧气供应对于住院病人来说是必不可少的。资源、运输和供应链的限制 新冠肺炎疫情的中断带来了一些独特的挑战。提供氧气的简单过程 在一家农村小医院、一家有临时医院的大医院里，补充变得非常具有挑战性 房间，在紧急运送到医院期间，在医院内运送感染病人期间，在发展中 医院资源不足的国家或出院病人在家就诊。我们建议开发一种新型氧气 通过电化学原理产生氧气的浓缩器。电化学氧气浓缩器 在大流行危机期间可以特别有价值，因为它相对于现有设备的独特优点，如 在合理的流速(1 LPM-5 LPM)下显著提高氧气纯度(&gt；99%)，降低功率消耗， 重量更轻，噪音更小，制造更容易。这是一个跨学科团队的合作成果， 在电化学、医疗器械设计和重症监护医学方面的专业知识。在这个为期两年的项目中，具体 目标1涉及医院内使用的电化学氧气浓缩器的开发，包括 电化学核心、流量控制系统和具有用户界面的外部塔。在具体目标2中， 我们将进行严格的测试，以记录功能原型-氧气的各种性能类别 浓度、流量、运行时间、电力消耗和用户界面--如世卫组织规范所规定的。 最后，我们将进行技术经济分析，以促进商业化和快速翻译 新型电化学富氧器的实践。

PROJECT SUMMARY Oxygen supply is essential for hospitalized patients. The limitation of resources, transport, and supply chain disruptions in the COVID-19 pandemic created some unique challenges. The simple process of providing O2 supplementation has become very challenging in a rural small hospital, a large hospital with makeshift hospital rooms, during emergency transport to the hospital, during in-hospital transport of infected patients, in developing nations with low-resource hospitals or at home for discharged patients. We propose to develop a novel oxygen concentrator that generates oxygen through electrochemical principles. The electrochemical oxygen concentrator can be especially valuable during the pandemic crisis owing to its unique merits over existing devices such as significantly higher oxygen purity (>99%) at reasonable flow rates (1 LPM – 5 LPM), lesser power consumption, less weight, less noise, and ease of manufacturing. This is a collaborative effort by an interdisciplinary team with expertise in electrochemistry, medical device design, and critical care medicine. In this two-year project, specific aim 1 involves the development of the electrochemical oxygen concentrator for in-hospital use, which includes the electrochemical core, the flow control system, and the external tower with a user interface. In specific aim 2, we will conduct rigorous tests to document various performance categories of the functional prototype – oxygen concentration, flow, operation time, power consumption, and user interface – as laid out by WHO specifications. And finally, we will conduct a technoeconomic analysis to facilitate commercialization and a quick translation to practice of the novel electrochemical oxygen concentrator.