IDENTIFYING DETERMINANTS FOR INDOOR AIR QUALITY AND THEIR HEALTH IMPACT IN ENVIRONMENTS FOR CHILDREN: MEASURES TO IMPROVE INDOOR AIR QUALITY AND REDUCE DISEASE BURDENS

儿童健康计划将整合健康、环境、技术和社会科学研究，以确定室内空气质量的决定因素，并评估它们对在校儿童所处环境的影响。我们将重点关注学校、家庭、体育馆和交通工具中的化学品、颗粒浓度、微生物和物理参数。这些环境的室内空气质量决定了儿童接受的剂量，并可能直接影响他们的健康和福祉。在欧洲三个城市的学校进行的一项环境流行病学研究和控制干预措施将评估空气中接触多种污染物对呼吸道感染、过敏以及神经和认知症状的健康影响。此外，剂量反应将通过一种新的体外细胞毒性测试管道进行评估。儿童健康联盟将涵盖令人印象深刻的地理和文化多样性，在来自北欧、中欧和南欧的七个欧洲国家开展有针对性的暴露测量运动和公民参与，并在澳大利亚采取干预措施。所有的项目吗?联合国儿童基金会的研究结果将汇集在儿童健康综合风险评估工具中，该工具将提供有关来源、排放、浓度、接触、剂量和儿童疾病之间相互作用的信息。此外，我们将开发用户友好和低成本的监测技术和战略（技术和行为），以改善室内空气质量和减少疾病负担。InChildHealth将为欧洲不同气候和社会环境下儿童所处的室内环境提供许多关于空气污染物及其主要来源的公平数据集。我们的研究结果将以指导方针、建议和培训材料的形式传播，这些材料部分是与儿童一起以公民科学的方式编写的。这些材料将支持学校的室内空气质量管理框架，促进室内空气质量管理，并广泛促进更健康的室内环境。

InChildHealth will integrate health, environmental, technical and social sciences research to identify determinants for Indoor Air Quality (IAQ) and evaluate their impact in environments occupied by school children. We will focus on chemicals, particle concentrations, microorganisms and physical parameters in schools, homes, sports halls and transport. The IAQ of these environments determines the dose received by the children and may directly influence their health and well-being. An environmental epidemiological study and controlled interventions conducted in schools in three European cities will assess the health effects of multipollutant airborne exposures on respiratory infections, allergies, and neurological and cognitional symptoms. In addition, dose-response will be evaluated with a novel cytotoxicity testing pipeline using in-vitro approaches. The InChildHealth consortium will cover an impressive variety of geographical and cultural diversity, with targeted exposure measurement campaigns and citizen involvement in seven European countries from Northern, Central and Southern Europe and interventions in Australia. All project?s results will converge in the InChildHealth Integrated Risk Assessment Tool, which will provide information on the interactions between the sources, emissions, concentrations, exposure, doses and disease for children. Besides, we will develop user-friendly and low-cost monitoring technologies and strategies (technical and behavioural) to improve IAQ and reduce disease burdens. InChildHealth will produce many FAIR datasets on air pollutants and their main sources for indoor environments occupied by children in different climatic and social settings in Europe. Our findings will be disseminated as guidelines, recommendations and training material partly developed with children in a citizen science approach. Such material will support the IAQ regulatory framework in schools, facilitate IAQ management, and broadly promote healthier indoors.