Juno

伤口的影响是巨大的：每年给NHS造成约56亿英镑的损失，造成约3.7万人死亡，感染导致永久性残疾，生活质量下降。伤口治疗的合并费用从每位患者每年5000英镑到11200英镑不等。Lugos正在开发一种系统，可以使用光学、光基技术即时准确地诊断感染并识别开放性伤口中的特定病原体。在病原体识别之后，该系统将提供治疗以根除伤口中的病原体，并立即确认治疗已被证明有效。该系统包含一个易于使用的手机应用程序和低成本设备，用于患者/护理人员在家中评估开放性伤口，以便在整个治疗过程中持续每天自我监测开放性伤口的愈合情况，并在任何感染变成慢性感染之前立即显示需要临床干预的时间。成功实施的影响将消除诊断的可变性，改善患者的预后并减少对抗生素的依赖。该系统将需要长达两年的时间来开发并进行测试和临床试验。与潜在投资者和客户的初步讨论引起了人们对这种独特方法的极大兴趣；然而，为了在这个早期阶段吸引私人投资者的资金，我们已经认识到，该系统和整体方法的示范将支持我们的沟通活动。_**Juno**_的主要目标是开发一个演示器和基本的工作基础设施，以便能够获得潜在投资者/用户的购买/支持，并为完整的系统开发提供有价值的反馈。Juno将采用现有技术来模拟完全开发的系统将如何在操作中使用。Juno项目将专注于开发一个功能齐全的演示器，利用资金开发一个使用伤口打印图像而不是体外样本的操作系统（一些图像包含隐藏的打印签名来模拟感染，一些图像显示一系列渐进的愈合伤口）。我们将开发一个示范移动应用程序和远程在线数据库，利用手机的摄像头实时捕捉图像，并参考数据库立即识别感染、未感染和逐渐愈合的伤口之间的差异。说明完全开发的系统将如何在使用中操作。我们将使用此演示系统来准备文献，图像和视频演示，以展示完全开发的系统将如何简单地工作，并使用此演示器亲自获得投资者的支持和潜在客户/用户的反馈。

The impact of wounds is significant: costing the NHS ~£5,600,000,000 p.a. and responsible for ~37,000 deaths, with infections leading to permanent disability and decreased quality of life. The conflated cost of wound treatment ranges from £5,000-£11,200 per patient/year.Lugos are developing a system to instantly & accurately diagnose infections and identify specific pathogens in open wounds using optical, light-based technologies. Following pathogen identification, the system will deliver treatment to eradicate pathogens in the wound and instantly confirm that the treatment has proved effective. The system incorporates an easy-to-use mobile phone app & low-cost device for evaluation of open-wounds by the patient/carer at home, to enable continuous daily self-monitoring of the healing of open wounds throughout treatment & instantly highlighting when clinical intervention is required, well before any infection becomes chronic.The impact of successful implementation will remove diagnostic variability, improved patient outcomes & lead to reduced antibiotic reliance. The system will take up to two years to develop & undergo testing & clinical trials.Initial discussions with potential investors and customers has raised significant interest in the unique approach; however, in order to attract private investor funding at this early stage we have recognised that a demonstrator of the system and the holistic approach would support our communication activities.The key objective of _**Juno**_ is to develop a demonstrator & basic, working infrastructure to be able to gain buy-in/support from potential investors/users & to provide valuable feedback to full system development. Juno will employ existing technologies to simulate how the fully developed system would be used in operationThe _**Juno**_ project will focus on developing a fully functional demonstrator, using the funding to develop an operational system using printed images of wounds instead of in-vitro samples (some images containing hidden printed signatures to simulate infection & some images demonstrating a progressive series of healing wounds). We will develop a demonstrator mobile app, and remote online-database,utilising the phone's camera to capture images in real-time and referring to the database to instantly identify differences between infected,non-infected and progressively healing wounds. Illustrating how the fully developed system would operate in use. We will use this demonstrator system to prepare literature, images & video demonstrations to show how simply the fully developed system will work & use this demonstrator in-person to gain buy-in from investors & feedback from potential customers/users.