Pilot Core

项目摘要(试点核心) 加速阿尔茨海默病人口研究中心(CAPRA)的首要目标是作为一个 国家资源，以促进和加速多学科研究，为各国政府的行动提供信息， 医疗保健系统和提供者可以采取措施来减轻AD/ADRD的社会、经济和健康负担。 试点核心将通过提供资金、资源和网络，为实现这一目标发挥核心作用 用于在Capra的专题研究领域进行试点研究的调查人员。试点研究提供了以下机会 测试有希望的假设，刺激研究人员合作，并为新的拨款生成初步数据。 但它们的规模较小，时间较短，难以有效完成并过渡到全面 学习。为了减少阿尔茨海默氏症患者和医疗保健研究的准入门槛，试点核心是 旨在不仅为飞行员提供资金，而且还提供获得专业知识、方法和在某些情况下获得数据的途径 确保成功。我们将征集和选择符合Capra的不同调查人员的试点研究 主题和最有机会发展为外部资助的研究项目并最具影响力 在人群健康方面了解和治疗阿尔茨海默氏症和相关痴呆。我们的目标是 征求多个学科的试点研究，包括过渡到AD/ADRD的资深调查人员 研究。我们将不仅向密歇根大学征集试点研究，还将向更广泛的领域征求意见 全国各地的研究团体。招标战略将利用现有的网络，例如 少数民族老龄化研究资源中心、国家临床学者项目和其他合作项目 与Capra领导层及其附属机构合作的团体。卡普拉不仅会资助有前途的飞行员 随着研究的深入，试点研究调查员将成为CAPRA不可或缺的一部分。他们将参与其他 Capra活动，创建了更广泛的痴呆症研究合作者网络，并正在收到 通过撰写完整的R01拨款建议书的过程进行指导。我们将利用数据、方法和 所有CAPRA合作者的经验，以提高其研究的科学性和潜在影响力。 我们将通过指导、研讨会和拨款撰写研讨会来实现这一目标。最终，我们的目标是将 来自多个学科的有才华的研究人员进入阿尔茨海默氏症研究并寻求创新合作 解决办法。

Project Abstract (Pilot Core) The overarching goal of the Center to Accelerate Population Research in Alzheimer’s (CAPRA) is to serve as a national resource to promote and accelerate multidisciplinary research that informs the actions governments, healthcare systems and providers can take to reduce the social, economic, and health burden of AD/ADRD. The Pilot Core will serve a central role for achieving that goal by providing funding, resources, and networking for investigators doing pilot studies in CAPRA’s thematic research areas. Pilot studies provide opportunities to test promising hypotheses, stimulate investigator collaborations, and generate preliminary data for new grants. But their small scale and short timeline can make it difficult to efficiently complete and to transition to full-scale studies. To reduce barriers to entry for Alzheimer’s population and healthcare research, the Pilot Core is designed to provide not only funding for pilots but also access to expertise, methods and in some cases data to ensure success. We will solicit and select pilot studies from a diverse set of investigators that fit CAPRA’s themes and have the best chance to develop into externally funded research projects and be most influential for understanding and treating Alzheimer’s disease and related dementias in population health. We aim to solicit pilot studies across many disciplines, including established investigators transitioning into AD/ADRD research. We will solicit pilot studies not only from the University of Michigan, but also from the broader research community around the country. The solicitation strategy will access existing networks, such as Resource Centers for Minority Aging Research, National Clinical Scholars programs, and other collaborative groups with whom the CAPRA leadership and affiliates work. CAPRA will not merely fund promising pilot studies, the Pilot Study Investigators will become an integral part of CAPRA. They will participate in other CAPRA activities, creating a wider network of dementia research collaborators, and also receive ongoing mentorship through the process of writing full R01 grant proposals. We will leverage data, methods, and experience across all CAPRA collaborators to enhance the science and potential influence of their research. We will achieve this through mentoring, seminars, and grant-writing workshops. Ultimately, our goal is to bring talented researchers from many disciplines into Alzheimer’s research and seek innovative collaborative solutions.