Switchable and stereocontrolled photoredox catalysis

该项目旨在开发新的催化合成反应，用于在温和条件下使用可见光快速和更直接地官能化有机化合物。一个综合的实验和计算方法将被用来设计有效的可见光光催化剂，保留标准的光氧化还原催化的优点，但具有额外的能力，拦截，从而控制，活性中间体在原位。这将使得能够控制光氧化还原反应中的立体化学-标准催化剂不可能-并建立其他有用的合成转化。这些策略将使制备有价值的有机分子更容易-高效，安全和具有成本效益。

This project aims to develop new catalytic synthetic reactions for the rapid and more direct functionalisation of organic compounds under mild conditions with the use of visible light. An integrated experimental and computational approach will be used to design potent visible-light photocatalysts that retain the advantages of standard photoredox catalysis but with the added ability to intercept and, thus control, reactive intermediates in situ. This will enable the control of stereochemistry in photoredox reactions – not possible with standard catalysts - and establish other useful synthetic transformations. These strategies will make it easier to prepare valuable classes of organic molecules – efficiently, safely, and cost-effectively.