Expanding the Evidence-Base for Prevention Strategies to Improve the Health of Women, Infants, and Families

项目摘要/摘要 贫穷的、受教育程度较低的、非裔美国人或土著美国人，或生活在农村或市中心的妇女， 更有可能经历严重的孕产妇发病率或死亡率或分娩低出生体重儿。因素 导致慢性病的健康差距也是在生命过程的早期造成的。的长期影响 怀孕和儿童早期健康是母婴健康的关键时期，在这一时期，干预措施可能 对成人健康和慢性病有很大影响。因为居住环境和社会经济地位 对结果的影响比健康行为和临床护理更大，对有效预防的研究 要么减少贫困，要么保护母亲免受其他有害的社会健康决定因素的战略， 婴儿和家庭也是一个紧迫的优先事项。拟议中的威斯康星大学的首要使命是- 麦迪逊预防研究中心(UWPRC)旨在改善低收入妇女、婴儿和 通过开展高质量的应用健康促进和疾病预防研究 着力实现健康公平。UWPRC将通过使用多学科校园来实现这一目标 研究人员、公共卫生从业者、社区和政府组织以及家庭 制定研究和翻译议程。议程将强调政策和系统战略 疾病预防控制中心健康影响金字塔的基础，那里有广泛的人口影响。UWPRC反映了一种 威斯康星大学麦迪逊医学院和公共卫生学院、贫困研究所和 人类生态学院。为了支持这项工作，UWPRC成立了一个管理小组， 聘请了校园内的核心教员，并建立了社区咨询委员会和翻译 合作伙伴面板。中心活动旨在构建强大的基础设施来支持和扩展协作 与社区成员合作，实现高质量和社区基础的干预、实施和 基于公共卫生实践的研究和翻译。首个核心中心研究项目“寻址” 威斯康星州家访项目中的产后抑郁症带来了一种以社区为基础的新方法 减少产妇抑郁的影响，总体上约有20%的新妈妈经历过抑郁， 威斯康星州近30%的低收入母亲关注婴儿发育和健康。核心项目负责人 调查员将与该中心合作，在联邦资助的家访中调整和完善翻译 计划，改善产妇抑郁症状和支持婴儿的有效干预措施 依恋。这所旗舰州立大学是全国第五大研究型大学，历史悠久 解决全州的需求(被称为威斯康星州的想法)。地理、社会经济、种族 和种族多样性使威斯康星州成为一个出色的现实世界环境，在其中开展社区参与 将支持广泛翻译到其他州和地区的预防研究。

PROJECT SUMMARY/ABSTRACT Women who are poor, less educated, African American or Native American, or live in rural or inner-city settings, are more likely to experience a severe maternal morbidity or mortality or deliver a low birthweight infant. Factors leading to health disparities around chronic disease are also set early in the life course. The long-term effects of pregnancy and early childhood point to maternal and child health as a key period when interventions may have great impact on adult health and chronic disease. Because the lived environment and socioeconomic status have a larger impact on outcomes than health behaviors and clinical care, research into effective prevention strategies that either reduce poverty or protect from other deleterious social determinants of health for mothers, infants and families are also an urgent priority. The overarching mission of the proposed University of Wisconsin- Madison Prevention Research Center (UWPRC) is to improve the health of low-income women, infants and families through the conduct of high-quality applied health promotion and disease prevention research with a focus on achieving health equity. The UWPRC will accomplish this by engaging multidisciplinary campus researchers, public health practitioners, community-based and governmental organizations and families to develop a research and translational agenda. The agenda will emphasize policy and systems strategies at the foundation of the CDC Health Impact Pyramid where there is broad population impact. The UWPRC reflects a partnership of the UW-Madison School of Medicine and Public Health, Institute for Research on Poverty, and the School of Human Ecology. To support this work, the UWPRC has established an Administrative Team, engaged core faculty from across campus, and developed a Community Advisory Board and Translational Partners Panel. Center activities are designed build a strong infrastructure to support and expand collaboration with community members and enable high quality and community grounded intervention, implementation, and public health practice-based research and translation. The initial core center research project “Addressing Postpartum Depression in Wisconsin Home Visiting Programs” brings a novel community-based approach to reducing the impact of maternal depression, experienced by approximately 20% of new mothers overall and nearly 30% of low income mothers in Wisconsin, on infant development and health. The core project Principal Investigator will work with the center to adapt and refine for translation, within federally-funded home visiting programs, an efficacious intervention that improves maternal depression symptoms and supports infant attachment. This flagship state university, the fifth largest research university in the country, has a long history of addressing needs across the state (known as the Wisconsin Idea). The geographic, socioeconomic, racial and ethnic diversity make Wisconsin an outstanding real world setting in which to conduct community-engaged prevention research that will support broad translation to other states and regions.