Biostatistics, Epidemiology, and Research Design Core

生物统计学、流行病学和研究设计核心项目摘要 大平原生物统计学、流行病学和研究设计（BERD）核心的目标是 CTR（GP IDEA-CTR）旨在开发进行高质量临床和转化研究的基础设施 (CTR)并加强在整个大的有竞争力的CTR计划和研究团队的发展 平原在最初的资助期间，BERD核心成功地利用其成员的专业知识， 为推进GP IDEA-CTR网络中的CTR研究提供必要的支持。BERD核心 在团队科学方法方面与其他核心密切合作，继续并扩大对以下方面的支持： 进一步推进CTR，并解决大平原地区的区域卫生优先事项。除了支持 科学研究和开发BERD方法研究，我们与所有核心和试点合作 支持研究设计培训、资助开发和早期职业CTR指导的计划 investigators. BERD的具体目标是：1）在研究设计、数据采集和 数据分析，以支持整个GP IDEA-CTR网络中的研究者和团队; 2）领导或促进 开发尖端的方法和工具，以满足GP IDEA的需求- CTR研究社区; 3）为GP IDEA-CTR研究者提供关于最佳 通过团队科学方法为CTR的全方位研究设计和分析提供策略; 4）提供 关于获取和利用卫生数据集的培训，以遵循区域卫生优先事项， 和实施稳健和关键的CTR。在实现这些目标的过程中，BERD核心发挥着重要作用 通过创造对关键专业知识、工具和 资源这种访问将有利于GP IDEA-CTR研究者成功进行CTR，并为GP IDEA- CTR早期职业调查员具有发展CTR职业的基本技能。

Biostatistics, Epidemiology, & Research Design Core Project Summary The objective of the Biostatistics, Epidemiology, and Research Design (BERD) Core of the Great Plains IDeA- CTR (GP IDeA-CTR) is to develop the infrastructure to conduct high-quality clinical and translational research (CTR) and enhance the development of competitive CTR programs and research teams across Great Plains. During the initial funding period, the BERD Core successfully leveraged its members' expertise to provide essential support to advance CTR research across the GP IDeA-CTR network. The BERD Core closely collaborates with the other Cores in team science approaches to continue and expand the support to advance CTR further and address regional health priorities of the Great Plains region. In addition to supporting scientific research and developing BERD methodology research, we collaborate with all the Cores and the Pilot Projects Program to support training in study design, grant development, and mentoring of early career CTR investigators. The BERD specific aims are 1) Consult and collaborate on study design, data acquisition, and data analysis to support investigators and teams throughout the GP IDeA-CTR network; 2) Lead or facilitate the development of cutting-edge methodologies and tools in response to the needs of the GP IDeA- CTR research community; 3) Provide education and mentoring to GP IDeA-CTR investigators on best strategies for study design and analysis for the full range of CTR through a team science approach; 4) Provide training on access and utilization of health data sets to follow regional health priorities to facilitate the design and implementation of robust and critical CTR. In achieving these aims, the BERD Core plays an essential role in transforming CTR in the Great Plains region by creating universal access to critical expertise, tools, and resources. This access will benefit GP IDeA-CTR investigators to conduct successful CTR and equip GP IDeA- CTR early career investigators with essential skills to develop their CTR careers.