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中文摘要
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概要/摘要-项目1。多特征、多尺度地图集 Berghia大脑项目的项目1是创建Berghia大脑的多尺度,多特征图谱, 周围神经丛Berghia的大脑体积很小,可以连续切片, 也只有很少的神经元, 特征和目录。为这项工作开发工具将有助于实现 BRAIN Initiative全面绘制人类大脑。Berghia大脑图谱将包含连接性, 神经解剖学和大脑中单个神经元的基因表达谱。它还将展示那些 中枢神经元与周围神经元和终末器官相连。周围神经丛本身 特征化和映射。这将有助于理解大脑和分布式外围设备如何相互作用。的 atlas将被用来追踪体感,嗅觉和视觉系统,以测试基本模型, 这些系统是如何组织的。这个项目将确定是否体细胞定位图存在于 个脑袋它还将决定嗅觉系统在没有肾小球的情况下是如何组织的。最后,它将审查 视觉的分布式多感官特性。
英文摘要
SUMMARY / ABSTRACT – Project 1. Multi-feature, Multi-scale Atlas Project 1 of the Berghia Brain Project is to create a multi-scale, multi-feature atlas of the Berghia brain and peripheral neural plexus. Berghia has a brain that is both physically small enough to be serially sectioned and reconstructed from electron micrographs and also has few enough neurons that they can be individually characterized and catalogued. Developing the tools for this undertaking will aid in the long term goal of the BRAIN Initiative to fully map the human brain. The Berghia brain atlas will contain the connectivity, neuroanatomy, and gene expression profile of individual neurons in the brain. It will also feature how those central neurons connect to neurons in periphery and to end organs. The peripheral plexus itself will be characterized and mapped. This will aid in understanding how a brain and a distributed periphery interact. The atlas will be used to trace out the somatosensory, olfactory, and visual systems to test fundamental models of how these systems are organized. This project will determine whether somatotopic maps are present in the brain. It will also determine how an olfactory system is organized without glomeruli. Finally, it will examine the distributed, multi-sensory nature of vision.
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A Connectomic Analysis of a Developing Brain Undergoing Neurogenesis
Berghia BRAIN project
Administration Core
Behavioral Analysis and Recording
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